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  • 👀 Eye Health News: Diet, Genes, & New Treatments

👀 Eye Health News: Diet, Genes, & New Treatments

5-min Weekly Digest

Happy Friday! ☕️ Celebrate Healthy Vision Month: Protect Your Eyes! Nourish your eyes with antioxidants and omega-3s found in colorful fruits, veggies, fish, and nuts. Exercise regularly, quit smoking, and moderate alcohol to reduce eye disease risk. Prioritize routine eye exams to detect early signs of disease and discuss family history with your doctor.

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“The purpose of our lives is to be happy.”

Dalai Lama

Eyecare

Apple Announces New Accessibility Features, Including Eye Tracking

Apple has announced a wave of new accessibility features coming to its devices later this year. These include Eye Tracking for navigating with just your eyes, Music Haptics for experiencing music through vibrations, Vocal Shortcuts for completing tasks with custom sounds, and Vehicle Motion Cues to reduce motion sickness. The company is also expanding accessibility options in CarPlay and visionOS, further demonstrating its commitment to inclusive design. READ MORE.

Early Color Limitations Boost Brain's Object Recognition

Early exposure to limited color information, similar to what newborns experience, may actually enhance the brain's ability to recognize objects in both color and black-and-white images. This adaptability, potentially rooted in early development, contrasts with individuals whose sight is restored later in life, who may overly rely on color cues and struggle with grayscale images. This finding suggests that early limitations in sensory input can be beneficial for overall perceptual development. READ MORE.

Protecting Vision in EYS-Associated Retinal Dystrophy

New research reveals that individuals with eyes shut homolog (EYS)-associated retinal dystrophy (EYS-RD) may experience light-induced photoreceptor cell death, particularly from blue light, due to the mislocalization of a key protein involved in photoresponse recovery. Mutations in the EYS gene are a leading cause of inherited retinal dystrophies. Avoiding phototoxicity could be a potential therapeutic approach for this inherited eye disease. READ MORE.

Jennifer Aniston's Dry Eye Lessons

Jennifer Aniston's experience with dry eye highlights the importance of recognizing common symptoms like irritated, itchy eyes, understanding its diverse causes ranging from hormonal changes to medications, and seeking diagnosis and appropriate treatment from an ophthalmologist to alleviate discomfort and manage the condition effectively. Read more.

Eat Your Way to Healthy Eyes

A diet rich in vitamins C and E, zinc, lutein, zeaxanthin, and omega-3 fatty acids may help protect your eyes from age-related macular degeneration, cataracts, and other eye conditions. Load up on leafy green vegetables, colorful fruits, nuts, seafood, and whole grains to give your eyes the nutrients they need to stay healthy. READ MORE.

Electrical 'Noise' Linked to Congenital Night Blindness

A Johns Hopkins study reveals that a specific mutation in the rhodopsin gene, responsible for light sensitivity in the eye, generates high-frequency electrical "noise." This noise disrupts the function of rod cells, critical for night vision, leading to congenital stationary night blindness. The findings may pave the way for new therapeutic interventions targeting this unusual electrical activity. READ MORE.

COVID-19 May Cause Eye Damage

Research reveals that the SARS-CoV-2 virus, responsible for COVID-19, can penetrate the blood-retinal barrier even in healthy individuals, potentially leading to inflammation and vision loss. Experts recommend that individuals diagnosed with COVID-19, including those without symptoms, consult an ophthalmologist to monitor for potential eye damage. READ MORE.

New Product Launch

FDA Approves First Interchangeable Biosimilar for Leading Eye Disease Treatment

Biocon Biologics has secured FDA approval for Yesafili™, the first interchangeable biosimilar to Eylea®, a leading treatment for various eye diseases including wet age-related macular degeneration (AMD). Yesafili™ has demonstrated comparable quality, safety, and efficacy to Eylea® and has already been approved in Europe and the UK. This approval marks Biocon Biologics' expansion into the U.S. ophthalmology market, offering a more affordable treatment option for the millions of Americans living with AMD. READ MORE.

KDB GLIDE® Expands Treatment for Glaucoma Patients

The FDA has cleared the KDB GLIDE® device for expanded use in treating glaucoma, now allowing it to be used during cataract surgery or as a standalone procedure. This versatile tool, backed by extensive clinical data, effectively reduces eye pressure by precisely removing tissue, offering a valuable new option for ophthalmologists and their patients. READ MORE.

Tech News

3D-Printed Eye Implants: A Vision for Personalized Eye Care

Researchers at the University of East Anglia have developed a groundbreaking resin for 3D printing customized intraocular lenses (IOLs). This innovation could revolutionize eye care by offering faster production, personalized designs, and potentially improved vision outcomes for patients with cataracts and refractive errors. READ MORE.

AI Enhances Dry Eye Diagnosis

Researchers have developed an AI-powered method to automate tear film break-up time (TBUT) measurement, a key indicator of dry eye disease. By analyzing slit lamp videos, the AI system accurately classifies frames into breakup and non-breakup categories, offering a more objective and reliable diagnosis compared to traditional methods. This advancement has the potential to improve dry eye diagnosis and management. READ MORE.

LLM Integration in Philippine Ophthalmology

While large language models (LLMs) offer innovative potential for ophthalmology, their implementation in the Philippines faces challenges like the lack of local ophthalmological data, limited funding for building LLMs, and the absence of a national regulatory safety net. To address these issues, experts must educate Filipinos on the proper use of LLMs, policymakers should regulate their introduction, and ophthalmologists should focus on local research and open access publishing to create an accurate Filipino database. READ MORE.

Research Updates

Low-Dose Aspirin and Age-Related Macular Degeneration

A recent study found that taking low-dose aspirin daily for three years did not significantly affect the development or progression of age-related macular degeneration (AMD) in older adults. This suggests that aspirin may not be a preventive measure for this common eye condition. READ MORE.

Corneal Graft Reversal Outcomes in European VISICORT Study

Corneal grafts that successfully overcome immune rejection maintain good visual function and structural integrity, regardless of initial risk factors or graft type, according to a European study. This promising finding offers valuable prognostic information for clinicians and realistic expectations for patients regarding corneal transplant outcomes. READ MORE.

Positive Framing Reduces Patient's Perceived Risk in Cataract Surgery

Framing cataract surgery risks positively significantly lowers patient's perceived risk compared to negative framing, highlighting the importance of communication style in informed decision-making. READ MORE.

How Neurons Build a 3-D Vascular Structure to Keep the Retina Healthy

Newly discovered perivascular neurons in the retina use a protein called PIEZO2 to sense cell contact and guide the formation of the intricate blood vessel lattice essential for vision. When this process is disrupted, blood flow is impaired, leading to neuronal degradation and increased vulnerability to stroke-like injuries. This groundbreaking research opens doors for potential therapies targeting neurodegenerative diseases and vascular disorders in both the eye and brain. READ MORE.

Clinical Trial Updates

Rezolute's Oral Drug Shows Promise in Treating Diabetic Macular Edema

Rezolute's RZ402, an oral medication, has demonstrated significant potential as a first-line, non-invasive treatment for diabetic macular edema (DME). Phase 2 clinical trial results showed a reduction in retinal swelling across all dosages, with a good safety profile. This breakthrough offers a convenient alternative to eye injections, potentially transforming DME treatment and improving patient outcomes. READ MORE

Omega-3 Supplements for Dry Eye: Trial Results Inconclusive

A recent randomized clinical trial investigated the effectiveness of re-esterified triglyceride (rTG) omega-3 fatty acid supplements in treating dry eye disease with meibomian gland dysfunction (MGD). The study found no significant difference between the omega-3 group and the control group receiving grape-seed oil in improving dry eye symptoms after 6 or 12 weeks. While the rTG form of omega-3 did not demonstrate a clear benefit in this trial, further research is needed to explore its potential role in managing dry eye associated with MGD. READ MORE.

Daily Red Light Therapy Shows Promise in Slowing Myopia in Children

A randomized clinical trial found that daily exposure to low-level red light (LLRL) for one year significantly slowed the progression of myopia and axial length elongation in children with mild to moderate nearsightedness, without any identified safety concerns. These findings suggest that LLRL could be a potential non-invasive treatment option for childhood myopia, but further research is needed to confirm its long-term efficacy and safety. READ MORE.

What Else to Skim

Travel Support Improves AMD Treatment Access

Reimbursing travel costs for patients with age-related macular degeneration (AMD) may significantly increase the number of eye injections they receive, regardless of their distance from the clinic, potentially improving long-term vision outcomes. This suggests that travel support programs could be a cost-effective way to enhance patient care and adherence to treatment. READ MORE.

Woman's Eye Infection Linked to Crocodile Meat

A woman in the Democratic Republic of the Congo developed a rare eye infection caused by a worm-like parasite after consuming crocodile meat. The parasite, a type of tongue worm, was surgically removed from behind her eyelid. This case highlights the importance of safe food preparation and hygiene practices when handling reptiles. READ MORE.

The Complexity of Eye Color

Eye color, a complex trait determined by 16 genes, goes beyond simple recessive or dominant inheritance. Blue eyes, linked to a single European ancestor, are not the rarest. Green eyes, found in only 2% of the population, vary in prevalence globally. Hazel eyes, a mix of gold, brown, and green, are considered the most complex, changing color based on light and clothing due to light reflection and varying melanin levels. READ MORE.

And for a laugh...

“What happens to a frog's car when it breaks down? It gets toad away.”

“Why did the frog call his insurance company? He had a jump in his car.” 😄 

Hope you enjoyed. 👍️ 

More news is coming your way next week!